Novel multiscale modeling tool applied to Pseudomonas aeruginosa biofilm formation.
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ABSTRACT:
SUBMITTER: Biggs MB
PROVIDER: S-EPMC3798466 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
Novel multiscale modeling tool applied to Pseudomonas aeruginosa biofilm formation.
Biggs Matthew B MB Papin Jason A JA
PloS one 20131017 10
Multiscale modeling is used to represent biological systems with increasing frequency and success. Multiscale models are often hybrids of different modeling frameworks and programming languages. We present the MATLAB-NetLogo extension (MatNet) as a novel tool for multiscale modeling. We demonstrate the utility of the tool with a multiscale model of Pseudomonas aeruginosa biofilm formation that incorporates both an agent-based model (ABM) and constraint-based metabolic modeling. The hybrid model ...[more]
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