Vitamin B(12) metabolism during pregnancy and in embryonic mouse models.
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ABSTRACT:
SUBMITTER: Moreno-Garcia MA
PROVIDER: S-EPMC3798919 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Publications
Vitamin B(12) metabolism during pregnancy and in embryonic mouse models.
Moreno-Garcia Maira A MA Rosenblatt David S DS Jerome-Majewska Loydie A LA
Nutrients 20130910 9
Vitamin B(12) (cobalamin, Cbl) is required for cellular metabolism. It is an essential coenzyme in mammals for two reactions: the conversion of homocysteine to methionine by the enzyme methionine synthase and the conversion of methylmalonyl-CoA to succinyl-CoA by the enzyme methylmalonyl-CoA mutase. Symptoms of Cbl deficiency are hematological, neurological and cognitive, including megaloblastic anaemia, tingling and numbness of the extremities, gait abnormalities, visual disturbances, memory lo ...[more]
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Project description:This SuperSeries is composed of the SubSeries listed below.
2021-02-25 | GSE167431 | GEO