Ontology highlight
ABSTRACT:
SUBMITTER: Mancina RM
PROVIDER: S-EPMC3799017 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Mancina Rosellina Margherita RM Burza Maria Antonella MA Maglio Cristina C Pirazzi Carlo C Sentinelli Federica F Incani Michela M Montalcini Tiziana T Pujia Arturo A Congiu Tiziana T Loche Sandro S Pilia Sabrina S Wiklund Olov O Borén Jan J Romeo Stefano S Baroni Marco Giorgio MG
Diabetes/metabolism research and reviews 20130701 5
<h4>Background</h4>Childhood obesity is a growing epidemic worldwide, and it is associated with metabolic complications, such as insulin resistance. Recently, a genetic variation (rs7607980) in the COBLL1 gene has been associated with lower insulin resistance in adults. The aim of the study was to investigate if the association between COBLL1 rs7607980 genetic variant and lower insulin resistance was present early in life.<h4>Methods</h4>This sequence variant was genotyped in 878 overweight and ...[more]