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Multivalent glyconanoparticles with enhanced affinity to the anti-viral lectin Cyanovirin-N.


ABSTRACT: Low-mannose (LM) structures were coupled to gold nanoparticles (Au NPs) to amplify the affinity of LMs with Cyanovirin-N (CV-N) lectins and to study the structures of CV-N variants CVN(Q50C) and CVN(MutDB).

SUBMITTER: Wang X 

PROVIDER: S-EPMC3800545 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature

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Multivalent glyconanoparticles with enhanced affinity to the anti-viral lectin Cyanovirin-N.

Wang Xin X   Matei Elena E   Deng Lingquan L   Ramström Olof O   Gronenborn Angela M AM   Yan Mingdi M  

Chemical communications (Cambridge, England) 20110630 30


Low-mannose (LM) structures were coupled to gold nanoparticles (Au NPs) to amplify the affinity of LMs with Cyanovirin-N (CV-N) lectins and to study the structures of CV-N variants CVN(Q50C) and CVN(MutDB). ...[more]

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