Ontology highlight
ABSTRACT:
SUBMITTER: Comas I
PROVIDER: S-EPMC3800747 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Comas Iñaki I Coscolla Mireia M Luo Tao T Borrell Sonia S Holt Kathryn E KE Kato-Maeda Midori M Parkhill Julian J Malla Bijaya B Berg Stefan S Thwaites Guy G Yeboah-Manu Dorothy D Bothamley Graham G Mei Jian J Wei Lanhai L Bentley Stephen S Harris Simon R SR Niemann Stefan S Diel Roland R Aseffa Abraham A Gao Qian Q Young Douglas D Gagneux Sebastien S
Nature genetics 20130901 10
Tuberculosis caused 20% of all human deaths in the Western world between the seventeenth and nineteenth centuries and remains a cause of high mortality in developing countries. In analogy to other crowd diseases, the origin of human tuberculosis has been associated with the Neolithic Demographic Transition, but recent studies point to a much earlier origin. We analyzed the whole genomes of 259 M. tuberculosis complex (MTBC) strains and used this data set to characterize global diversity and to r ...[more]