Dataset Information

Size-fractionated particle number concentrations and daily mortality in a Chinese city.

ABSTRACT:

Background

Associations between airborne particles and health outcomes have been documented worldwide; however, there is limited information regarding health effects associated with different particle sizes.

Objectives

We explored the association between size-fractionated particle number concentrations (PNCs) and daily mortality in Shenyang, China.

Methods

We collected daily data on cause-specific mortality and PNCs for particles measuring 0.25-10 ?m in diameter between 1 December 2006 and 30 November 2008. We used quasi-Poisson regression generalized additive models to estimate associations between PNCs and mortality, and we used natural spline smoothing functions to adjust for time-varying covariates and long-term and seasonal trends.

Results

Mean numbers of daily deaths were 67, 32, and 7 for all natural causes, cardiovascular diseases, and respiratory diseases, respectively. Interquartile range (IQR) increases in PNCs for particles measuring 0.25-0.50 ?m were significantly associated with total and cardiovascular mortality, but not respiratory mortality. Effect estimates were larger for PNCs during the warm season than the cool season, and increased with decreasing particle size. IQR increases in PNCs of 0.25-0.28 ?m, 0.35-0.40 ?m, and 0.45-0.50 ?m particles were associated with 2.41% (95% CI: 1.23, 3.58%), 1.31% (95% CI: 0.52, 2.09%), and 0.45% (95% CI: 0.04, 0.87%) higher total mortality, respectively. Associations were generally stable after adjustment for mass concentrations of ambient particles and gaseous pollutants.

Conclusions

Our findings suggest that particles < 0.5 ?m in diameter may be most responsible for adverse health effects of particulate air pollution and that adverse health effects may increase with decreasing particle size.

SUBMITTER: Meng X

PROVIDER: S-EPMC3801202 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature

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Publications

Size-fractionated particle number concentrations and daily mortality in a Chinese city.

Meng Xia X Ma Yanjun Y Chen Renjie R Zhou Zhijun Z Chen Bingheng B Kan Haidong H

Environmental health perspectives 20130813 10

<h4>Background</h4>Associations between airborne particles and health outcomes have been documented worldwide; however, there is limited information regarding health effects associated with different particle sizes.<h4>Objectives</h4>We explored the association between size-fractionated particle number concentrations (PNCs) and daily mortality in Shenyang, China.<h4>Methods</h4>We collected daily data on cause-specific mortality and PNCs for particles measuring 0.25-10 μm in diameter between 1 D ...[more]

PMID: 23942310

Similar Datasets

Project description:BACKGROUND:Although epidemiologic studies have shown associations between particle mass and daily mortality, evidence on other particle metrics is weak. OBJECTIVES:We investigated associations of size-specific particle number concentration (PNC) and lung-deposited particle surface area concentration (PSC) with cause-specific daily mortality in contrast to PM10. METHODS:We used time-series data (March 2009-December 2014) on daily natural, cardiovascular, and respiratory mortality (NM, CVM, RM) of three adjacent cities in the Ruhr Area, Germany. Size-specific PNC (electric mobility diameter of 13.3-750?nm), PSC, and PM10 were measured at an urban background monitoring site. In single- and multipollutant Poisson regression models, we estimated percentage change (95% confidence interval) [% (95% CI)] in mortality per interquartile range (IQR) in exposure at single-day (0-7) and aggregated lags (0-1, 2-3, 4-7), accounting for time trend, temperature, humidity, day of week, holidays, period of seasonal population decrease, and influenza. RESULTS:PNC100-750 and PSC were highly correlated and had similar immediate (lag0-1) and delayed (lag4-7) associations with NM and CVM, for example, 1.12% (95% CI: 0.09, 2.33) and 1.56% (95% CI: 0.22, 2.92) higher NM with IQR increases in PNC100-750 at lag0-1 and lag4-7, respectfully, which were slightly stronger then associations with IQR increases in PM10. Positive associations between PNC and NM were strongest for accumulation mode particles (PNC 100-500?nm), and for larger UFPs (PNC 50-100?nm). Associations between NM and PNC<100 changed little after adjustment for O3 or PM10, but were more sensitive to adjustment for NO2. CONCLUSION:Size-specific PNC (50-500?nm) and lung-deposited PSC were associated with natural and cardiovascular mortality in the Ruhr Area. Although associations were similar to those estimated for an IQR increase in PM10, particle number size distributions can be linked to emission sources, and thus may be more informative for potential public health interventions. Moreover, PSC could be used as an alternative metric that integrates particle size distribution as well as deposition efficiency. https://doi.org/10.1289/EHP2054.

Dataset Information

Size-fractionated particle number concentrations and daily mortality in a Chinese city.

Background

Objectives

Methods

Results

Conclusions

Publications

Size-fractionated particle number concentrations and daily mortality in a Chinese city.

Similar Datasets

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