Personalizing therapies for gastric cancer: molecular mechanisms and novel targeted therapies.
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ABSTRACT:
SUBMITTER: Luis M
PROVIDER: S-EPMC3801309 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Publications
Personalizing therapies for gastric cancer: molecular mechanisms and novel targeted therapies.
Luis Michael M Tavares Ana A Carvalho Liliana S LS Lara-Santos Lúcio L Araújo António A de Mello Ramon Andrade RA
World journal of gastroenterology 20131001 38
Globally, gastric cancer is the 4(th) most frequently diagnosed cancer and the 2(nd) leading cause of death from cancer, with an estimated 990000 new cases and 738000 deaths registered in 2008. In the advanced setting, standard chemotherapies protocols acquired an important role since last decades in prolong survival. Moreover, recent advances in molecular therapies provided a new interesting weapon to treat advanced gastric cancer through anti-human epidermal growth factor receptor 2 (HER2) the ...[more]
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