Ontology highlight
ABSTRACT:
SUBMITTER: Raposo RA
PROVIDER: S-EPMC3807358 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Raposo Rui André Saraiva RA Abdel-Mohsen Mohamed M Bilska Miroslawa M Montefiori David C DC Nixon Douglas F DF Pillai Satish K SK
Journal of virology 20130821 21
Expression of cell-intrinsic antiviral factors suppresses HIV-1 replication. We hypothesized that cellular activation modulates host restriction and susceptibility to HIV-1 infection. We measured the gene expression of 34 antiviral factors in healthy peripheral blood mononuclear cells (PBMC). Cellular activation induced expression of interferon-stimulated gene 15 (ISG15), tripartite motif 5α (TRIM5α), bone marrow stromal cell antigen 2 (BST-2)/tetherin, and certain apolipoprotein B mRNA editing ...[more]