AIDS alters the commensal plasma virome.
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ABSTRACT:
SUBMITTER: Li L
PROVIDER: S-EPMC3807392 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Publications
AIDS alters the commensal plasma virome.
Li Linlin L Deng Xutao X Linsuwanon Piyada P Bangsberg David D Bwana Mwebesa Bosco MB Hunt Peter P Martin Jeffrey N JN Deeks Steven G SG Delwart Eric E
Journal of virology 20130731 19
We compared the plasma viromes of HIV-infected subjects with low versus high CD4(+) T cell counts from the United States and Uganda by using deep sequencing and detected HIV, hepatitis C virus, hepatitis B virus, GB virus C, anellovirus, and human endogenous retrovirus (HERV) reads. An increase in the proportion of reads for anelloviruses, a family of highly prevalent and genetically diverse human viruses, was seen in subjects with AIDS from both countries. The proportion of endogenous human ret ...[more]
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