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Gene Expression Profiles at Moxibustioned Site (ST36): A Microarray Analysis.


ABSTRACT: As a major alternative therapy in Traditional Chinese Medicine, it has been demonstrated that moxibustion could generate a series of molecular events in blood, spleen, and brain, and so forth. However, what would happen at the moxibustioned site remained unclear. To answer this question, we performed a microarray analysis with skin tissue taken from the moxibustioned site also Zusanli acupoint (ST36) where 15-minute moxibustion stimulation was administrated. The results exhibited 145 upregulated and 72 downregulated genes which responded immediately under physiological conditions, and 255 upregulated and 243 downregulated genes under pathological conditions. Interestingly, most of the pathways and biological processes of the differentially expressed genes (DEGs) under pathological conditions get involved in immunity, while those under physiological conditions are involved in metabolism.

SUBMITTER: Yin HY 

PROVIDER: S-EPMC3807720 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature

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Gene Expression Profiles at Moxibustioned Site (ST36): A Microarray Analysis.

Yin Hai-Yan HY   Tang Yong Y   Lu Sheng-Feng SF   Luo Ling L   Wang Jia-Ping JP   Liu Xu-Guang XG   Yu Shu-Guang SG  

Evidence-based complementary and alternative medicine : eCAM 20130922


As a major alternative therapy in Traditional Chinese Medicine, it has been demonstrated that moxibustion could generate a series of molecular events in blood, spleen, and brain, and so forth. However, what would happen at the moxibustioned site remained unclear. To answer this question, we performed a microarray analysis with skin tissue taken from the moxibustioned site also Zusanli acupoint (ST36) where 15-minute moxibustion stimulation was administrated. The results exhibited 145 upregulated  ...[more]

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