Ontology highlight
ABSTRACT:
SUBMITTER: Balic M
PROVIDER: S-EPMC3809995 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Balic Marija M Williams Anthony A Lin Henry H Datar Ram R Cote Richard J RJ
Annual review of medicine 20121018
Circulating tumor cells (CTCs) represent a surrogate biomarker of hematogenous metastases. In recent years, their detection has gained increasing interest. There is ample evidence regarding the ability to detect CTCs and their prognostic relevance, but their demonstrated predictive value in therapeutic response monitoring is clinically even more meaningful. Many clinical trials in the early and metastatic cancer setting now include CTCs as a monitoring parameter, and numerous translational studi ...[more]