Ontology highlight
ABSTRACT:
SUBMITTER: Handke LD
PROVIDER: S-EPMC3810276 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Handke Luke D LD Hawkins Julio C JC Miller Alita A AA Jansen Kathrin U KU Anderson Annaliesa S AS
PloS one 20131028 10
Staphylococcus aureus is a successful human pathogen that has developed several approaches to evade the immune system, including resistance strategies to prevent oxidative killing by immune cells. One mechanism by which this evasion occurs is by production of superoxide dismutase enzymes, which require manganese as a cofactor. Manganese is acquired by the manganese transporter MntABC. One component of this operon, MntC, has been proposed as a potential vaccine candidate due to its early in vivo ...[more]