Ontology highlight
ABSTRACT:
SUBMITTER: Chen XJ
PROVIDER: S-EPMC3811608 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Microbiology and molecular biology reviews : MMBR 20130901 3
Homologous recombination is a universal process, conserved from bacteriophage to human, which is important for the repair of double-strand DNA breaks. Recombination in mitochondrial DNA (mtDNA) was documented more than 4 decades ago, but the underlying molecular mechanism has remained elusive. Recent studies have revealed the presence of a Rad52-type recombination system of bacteriophage origin in mitochondria, which operates by a single-strand annealing mechanism independent of the canonical Re ...[more]