Erythroid development in the mammalian embryo.
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ABSTRACT:
SUBMITTER: Baron MH
PROVIDER: S-EPMC3812334 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Publications
Erythroid development in the mammalian embryo.
Baron Margaret H MH Vacaru Andrei A Nieves Johnathan J
Blood cells, molecules & diseases 20130807 4
Erythropoiesis is the process by which progenitors for red blood cells are produced and terminally differentiate. In all vertebrates, two morphologically distinct erythroid lineages (primitive, embryonic, and definitive, fetal/adult) form successively within the yolk sac, fetal liver, and marrow and are essential for normal development. Red blood cells have evolved highly specialized functions in oxygen transport, defense against oxidation, and vascular remodeling. Here we review key features of ...[more]
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