Ontology highlight
ABSTRACT:
SUBMITTER: Kurtenbach S
PROVIDER: S-EPMC3813626 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Kurtenbach Stefan S Wewering Sonja S Hatt Hanns H Neuhaus Eva M EM Lübbert Hermann H
PloS one 20131030 10
Various genetic or toxin-induced mouse models are frequently used for investigation of early PD pathology. Although olfactory impairment is known to precede motor symptoms by years, it is not known whether it is caused by impairments in the brain, the olfactory epithelium, or both. In this study, we investigated the olfactory function in three genetic Parkinson's disease (PD) mouse models and mice treated with MPTP intraperitoneally and intranasally. To investigate olfactory function, we perform ...[more]