Ontology highlight
ABSTRACT:
SUBMITTER: Babiano R
PROVIDER: S-EPMC3814368 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Babiano Reyes R Badis Gwenael G Saveanu Cosmin C Namane Abdelkader A Doyen Antonia A Díaz-Quintana Antonio A Jacquier Alain A Fromont-Racine Micheline M de la Cruz Jesús J
Nucleic acids research 20130813 20
Ribosome biogenesis requires >300 assembly factors in Saccharomyces cerevisiae. Ribosome assembly factors Imp3, Mrt4, Rlp7 and Rlp24 have sequence similarity to ribosomal proteins S9, P0, L7 and L24, suggesting that these pre-ribosomal factors could be placeholders that prevent premature assembly of the corresponding ribosomal proteins to nascent ribosomes. However, we found L7 to be a highly specific component of Rlp7-associated complexes, revealing that the two proteins can bind simultaneously ...[more]