Mining patterns of adverse events using aggregated clinical trial results.
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ABSTRACT:
SUBMITTER: Luo Z
PROVIDER: S-EPMC3814483 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
Mining patterns of adverse events using aggregated clinical trial results.
Luo Zhihui Z Zhang Guo-Qiang GQ Xu Rong R
AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science 20130318
Adverse event reports contain the most important metrics for evaluating the hazards, harms, and risks of a clinical intervention. In this paper, we present an exploratory study of discovering internal association patterns between adverse events. By taking advantage of the published trials reports on ClinicalTrials.gov, we developed an automatic pipeline to create a Clinical Trial Adverse Event Database (cTAED), which currently stores 4,317 clinical trial reports and 11,362 adverse events. The as ...[more]
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