Ontology highlight
ABSTRACT:
SUBMITTER: Gajda MJ
PROVIDER: S-EPMC3817170 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Gajda Michal Jan MJ Martinez Zapien Denise D Uchikawa Emiko E Dock-Bregeon Anne-Catherine AC
PloS one 20131104 11
We propose a novel fragment assembly method for low-resolution modeling of RNA and show how it may be used along with small-angle X-ray solution scattering (SAXS) data to model low-resolution structures of particles having as many as 12 independent secondary structure elements. We assessed this model-building procedure by using both artificial data on a previously proposed benchmark and publicly available data. With the artificial data, SAXS-guided models show better similarity to native structu ...[more]