Ontology highlight
ABSTRACT:
SUBMITTER: Marcia M
PROVIDER: S-EPMC3817690 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Marcia Marco M Humphris-Narayanan Elisabeth E Keating Kevin S KS Somarowthu Srinivas S Rajashankar Kanagalaghatta K Pyle Anna Marie AM
Acta crystallographica. Section D, Biological crystallography 20131012 Pt 11
Structured RNA molecules are key players in ensuring cellular viability. It is now emerging that, like proteins, the functions of many nucleic acids are dictated by their tertiary folds. At the same time, the number of known crystal structures of nucleic acids is also increasing rapidly. In this context, molecular replacement will become an increasingly useful technique for phasing nucleic acid crystallographic data in the near future. Here, strategies to select, create and refine molecular-repl ...[more]