Ontology highlight
ABSTRACT:
SUBMITTER: Lundgren RJ
PROVIDER: S-EPMC3819219 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20130121 9
Pin the amine on the gamma: A new method has been developed for the γ-addition of nitrogen nucleophiles to γ-substituted alkynoates or allenoates through intra- and intermolecular processes that are catalyzed by spirophosphine 1. An asymmetric version of this reaction affords enantioenriched pyrrolidines, indolines, and γ-amino-α,β-unsaturated carbonyl compounds. ...[more]