A comparison of Y-chromosomal lineage dating using either resequencing or Y-SNP plus Y-STR genotyping.
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ABSTRACT:
SUBMITTER: Wei W
PROVIDER: S-EPMC3820021 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Publications
A comparison of Y-chromosomal lineage dating using either resequencing or Y-SNP plus Y-STR genotyping.
Wei Wei W Ayub Qasim Q Xue Yali Y Tyler-Smith Chris C
Forensic science international. Genetics 20130613 6
We have compared phylogenies and time estimates for Y-chromosomal lineages based on resequencing ∼9 Mb of DNA and applying the program GENETREE to similar analyses based on the more standard approach of genotyping 26 Y-SNPs plus 21 Y-STRs and applying the programs NETWORK and BATWING. We find that deep phylogenetic structure is not adequately reconstructed after Y-SNP plus Y-STR genotyping, and that times estimated using observed Y-STR mutation rates are several-fold too recent. In contrast, an ...[more]
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