Evaluation of PRSS56 in Chinese subjects with high hyperopia or primary angle-closure glaucoma.
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ABSTRACT:
SUBMITTER: Jiang D
PROVIDER: S-EPMC3820428 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
Evaluation of PRSS56 in Chinese subjects with high hyperopia or primary angle-closure glaucoma.
Jiang Dan D Yang Zhikuan Z Li Shiqiang S Xiao Xueshan X Jia Xiaoyun X Wang Panfeng P Guo Xiangming X Liu Xing X Zhang Qingjiong Q
Molecular vision 20131107
<h4>Purpose</h4>Mouse serine protease 56 (Prss56) mutants show a phenotype of angle-closure glaucoma with a shortened ocular axial length. Mutations in the human PRSS56 gene are associated with posterior microphthalmia and nanopthalmos. In this study, variations in PRSS56 were evaluated in patients with either primary angle-closure glaucoma (PACG) or high hyperopia.<h4>Methods</h4>A total of 561 participants were enrolled in this study, including 189 individuals with PACG, 110 individuals with s ...[more]
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