Porcine synapsin 1: SYN1 gene analysis and functional characterization of the promoter.
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ABSTRACT:
SUBMITTER: Hedegaard C
PROVIDER: S-EPMC3821028 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
Porcine synapsin 1: SYN1 gene analysis and functional characterization of the promoter.
Hedegaard Claus C Kjaer-Sorensen Kasper K Madsen Lone Bruhn LB Henriksen Carina C Momeni Jamal J Bendixen Christian C Oxvig Claus C Larsen Knud K
FEBS open bio 20131007
Synapsin 1 (SYN1) is a phosphoprotein involved in nerve signal transmission. The porcine SYN1 promoter orthologue was cloned and characterized to provide a means of expressing a transgene specifically in neurons. The nucleotide sequence of the promoter displayed a high degree of conservation of elements responsible for neuron-specific expression. Expression analysis of SYN1 demonstrated presence of transcript during embryonic development. Analysis of GFP expression in transgenic zebrafish embryo ...[more]
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