Ontology highlight
ABSTRACT:
SUBMITTER: Ralston KS
PROVIDER: S-EPMC3821760 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
Ralston Katherine S KS Kabututu Zakayi P ZP Melehani Jason H JH Oberholzer Michael M Hill Kent L KL
Annual review of microbiology 20090101
African trypanosomes are devastating human and animal pathogens. Trypanosoma brucei rhodesiense and T. b. gambiense subspecies cause the fatal human disease known as African sleeping sickness. It is estimated that several hundred thousand new infections occur annually and the disease is fatal if untreated. T. brucei is transmitted by the tsetse fly and alternates between bloodstream-form and insect-form life cycle stages that are adapted to survive in the mammalian host and the insect vector, re ...[more]