Dataset Information

Prevalence and associated factors of microalbuminuria in Chinese individuals without diabetes: cross-sectional study.

ABSTRACT:

Objective

To investigate the prevalence of microalbuminuria (MAU) among Chinese individuals without diabetes and the relationship between MAU and metabolic factors, individual socioeconomic status (SES), and regional economic development level.

Design

Cross-sectional study of prevalence of MAU.

Setting

152 urban street districts and 112 rural villages from northeast, north, east, south central, northwest and southwest China.

Participants

46 239 participants were recruited using a multistage stratified sampling design from 2007 to 2008. A total of 41 290 participants without diabetes determined by oral glucose tolerance test were included in the present study. Urine albumin/creatinine ratio results of 35 430 individuals were available.

Primary and secondary outcome measures

Positive detection of MAU was determined using an ACR of 22.1-299.9 mg/g in men 30.9-299.9 mg/g in women.

Results

The prevalence of MAU in men was 22.4% and 24.5% in women. In developed, intermediate-developed and under-developed areas, the prevalence of MAU in men was 20.7%, 21.9% and 32.5%, respectively; in women the prevalence was 19.6%, 26.0% and 29.5%, respectively. The prevalence of MAU increased as the number of metabolic disorders present increased, and as the number of lower SES components increased (farmer, below university education level and low income). Prevalence of MAU in developed and intermediate developed areas had adjusted risk ratios of 0.52 (95% CI 0.42 to 0.60) and 0.65 (95% CI 0.57 to 0.76), respectively. Multivariate logistic analyses demonstrated MAU was strongly associated with older age, high-blood pressure, higher blood glucose low education level, low occupational level and residence in under-developed region.

Conclusions

Several factors had independent correlations to MAU in China: older age, metabolic abnormalities, lower SES level and living in economically under-developed areas, which encourage the development of strategies to lower the risk for MAU in these susceptible populations.

SUBMITTER: Xiao J

PROVIDER: S-EPMC3822315 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature

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Publications

Prevalence and associated factors of microalbuminuria in Chinese individuals without diabetes: cross-sectional study.

Xiao Jianzhong J Xing Xiaoyan X Lu Juming J Weng Jianping J Jia Weiping W Ji Linong L Shan Zhongyan Z Liu Jie J Tian Haoming H Ji Qiuhe Q Zhu Dalong D Ge Jiapu J Chen Gang G Chen Li L Guo Xiaohui X Zhao Zhigang Z Li Qiang Q Zhou Zhiguang Z Yang Zhaojun Z Shan Guangliang G He Jiang J Yang Wenying W

BMJ open 20131104 11

<h4>Objective</h4>To investigate the prevalence of microalbuminuria (MAU) among Chinese individuals without diabetes and the relationship between MAU and metabolic factors, individual socioeconomic status (SES), and regional economic development level.<h4>Design</h4>Cross-sectional study of prevalence of MAU.<h4>Setting</h4>152 urban street districts and 112 rural villages from northeast, north, east, south central, northwest and southwest China.<h4>Participants</h4>46 239 participants were recr ...[more]

PMID: 24189077

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Dataset Information

Prevalence and associated factors of microalbuminuria in Chinese individuals without diabetes: cross-sectional study.

Objective

Design

Setting

Participants

Primary and secondary outcome measures

Results

Conclusions

Publications

Prevalence and associated factors of microalbuminuria in Chinese individuals without diabetes: cross-sectional study.

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