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ABSTRACT:
SUBMITTER: Reinharz V
PROVIDER: S-EPMC3822367 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Reinharz Vladimir V Ponty Yann Y Waldispühl Jérôme J
Journal of computational biology : a journal of computational molecular cell biology 20131017 11
The analysis of the sequence-structure relationship in RNA molecules is not only essential for evolutionary studies but also for concrete applications such as error-correction in next generation sequencing (NGS) technologies. The prohibitive sizes of the mutational and conformational landscapes, combined with the volume of data to process, require efficient algorithms to compute sequence-structure properties. In this article, we address the correction of NGS errors by calculating which mutations ...[more]