Ontology highlight
ABSTRACT:
SUBMITTER: Chao KC
PROVIDER: S-EPMC3822693 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Chao Kuo-Ching KC Yang Hui-Tai HT Chen Min-Wei MW
Journal of cellular and molecular medicine 20120801 8
The purpose of this study was to investigate how human umbilical cord mesenchymal stem cells (HUMSCs) affect breast cancer tumourigenesis. To observe the influence of HUMSCs on tumourigenesis in vitro, we performed a co-culture of MDA MB-231 breast cancer cells with HUMSCs, and a result of HUMSCs on tumourigenesis in vivo was achieved by injection of HUMSCs into nonobese diabetic/severe combined immunodeficient mice following tumour establishment with MDA-MB231. During the co-culture, apoptosis ...[more]