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Glutathione and thioredoxin type 1 cooperatively denitrosate HepG2 cells-derived cytosolic S-nitrosoproteins.


ABSTRACT: In this study, we present experimental evidence that glutathione acts in concert with human thioredoxin type 1 in the denitrosation of cytosolic S-nitrosoproteins (PSNOs) from HepG2 cells.

SUBMITTER: Stoyanovsky DA 

PROVIDER: S-EPMC3824615 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature

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Glutathione and thioredoxin type 1 cooperatively denitrosate HepG2 cells-derived cytosolic S-nitrosoproteins.

Stoyanovsky Detcho A DA   Scott Melanie J MJ   Billiar Timothy R TR  

Organic & biomolecular chemistry 20130701 27


In this study, we present experimental evidence that glutathione acts in concert with human thioredoxin type 1 in the denitrosation of cytosolic S-nitrosoproteins (PSNOs) from HepG2 cells. ...[more]

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