Ten years of progress in the Hokkaido birth cohort study on environment and children's health: cohort profile--updated 2013.

ABSTRACT: The Hokkaido Study on Environment and Children's Health is an ongoing cohort study that began in 2002. The study consists of two prospective birth cohorts, the Sapporo cohort (n = 514) and the Hokkaido large-scale cohort (n = 20,940). The primary goals of this study are to first examine the potential negative effects of perinatal environmental chemical exposures on birth outcomes, including congenital malformations and growth retardation; second, to evaluate the development of allergies, infectious diseases and neurodevelopmental disorders and perform longitudinal observations of the children's physical development to clarify the causal relationship between these outcomes and environmental chemicals; third, to identify individuals genetically susceptible to environmental chemicals; finally

SUBMITTER: Kishi R 

PROVIDER: S-EPMC3824728 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature