Ontology highlight
ABSTRACT:
SUBMITTER: Hisha H
PROVIDER: S-EPMC3828633 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Hisha Hiroko H Tanaka Toshihiro T Kanno Shohei S Tokuyama Yoko Y Komai Yoshihiro Y Ohe Shuichi S Yanai Hirotsugu H Omachi Taichi T Ueno Hiroo H
Scientific reports 20131115
Despite the strong need for the establishment of a lingual epithelial cell culture system, a simple and convenient culture method has not yet been established. Here, we report the establishment of a novel lingual epithelium organoid culture system using a three-dimensional matrix and growth factors. Histological analyses showed that the generated organoids had both a stratified squamous epithelial cell layer and a stratum corneum. Very recently, we showed via a multicolor lineage tracing method ...[more]