Ontology highlight
ABSTRACT:
SUBMITTER: Gonzalez Arbelaez LF
PROVIDER: S-EPMC3830772 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
González Arbeláez Luisa F LF Pérez Núñez Ignacio A IA Mosca Susana M SM
BioMed research international 20131030
The aim of this study was to examine the effects of GSK-3 β inhibitors compared with PRE and POS in spontaneously hypertensive rats (SHR). Isolated hearts were submitted to the following protocols: IC: 45 min global ischemia (GI) and 1-hour reperfusion (R); PRE: a cycle of 5 min GI and 10 minutes of R prior to 45 min GI; POS: three cycles of 30 sec GI/30 sec R at the start of R. Other hearts received lithium chloride (LiCl) or indirubin-3'-monoxime,5-iodo-(IMI) as GSK-3 β inhibitors. All interve ...[more]