Ontology highlight
ABSTRACT:
SUBMITTER: Gerdemann U
PROVIDER: S-EPMC3831033 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Gerdemann Ulrike U Katari Usha L UL Papadopoulou Anastasia A Keirnan Jacqueline M JM Craddock John A JA Liu Hao H Martinez Caridad A CA Kennedy-Nasser Alana A Leung Kathryn S KS Gottschalk Stephen M SM Krance Robert A RA Brenner Malcolm K MK Rooney Cliona M CM Heslop Helen E HE Leen Ann M AM
Molecular therapy : the journal of the American Society of Gene Therapy 20130620 11
Adoptive transfer of virus-specific T cells can prevent and treat serious infections with Epstein-Barr virus (EBV), cytomegalovirus (CMV), and adenovirus (Adv) after allogeneic hematopoietic stem cell transplant. It has, however, proved difficult to make this approach widely available since infectious virus and viral vectors are required for T cell activation, followed by an intensive and prolonged culture period extending over several months. We now show that T cells targeting a range of viral ...[more]