Ontology highlight
ABSTRACT:
SUBMITTER: Pelletier C
PROVIDER: S-EPMC3832135 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Expert review of molecular diagnostics 20100901 6
MicroRNAs (miRNAs) are well established as global gene regulators and thus, slight alterations in miRNA levels as well as their ability to regulate their targets may cause important cellular changes leading to cancer risk. 3´ untranslated region (UTR) miRNA binding site single nucleotide polymorphisms (SNPs) have added another layer of possible genetic variation involved in the complex process of oncogenesis. Identifying these key genetically inherited effectors of miRNA functioning has improved ...[more]