Ontology highlight
ABSTRACT:
SUBMITTER: Juliano C
PROVIDER: S-EPMC3832951 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Juliano Celina C Wang Jianquan J Lin Haifan H
Annual review of genetics 20110919
The topipotency of the germline is the full manifestation of the pluri- and multipotency of embryonic and adult stem cells, thus the germline and stem cells must share common mechanisms that guarantee their multipotentials in development. One of the few such known shared mechanisms is represented by Piwi proteins, which constitute one of the two subfamilies of the Argonaute protein family. Piwi proteins bind to Piwi-interacting RNAs (piRNAs) that are generally 26 to 31 nucleotides in length. Bot ...[more]