Ontology highlight
ABSTRACT:
SUBMITTER: Baliram R
PROVIDER: S-EPMC3836071 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Baliram R R Chow A A Huber A K AK Collier L L Ali M R MR Morshed S A SA Latif R R Teixeira A A Merad M M Liu L L Sun L L Blair H C HC Zaidi M M Davies T F TF
Endocrinology 20131018 12
It is now firmly established that TSH may influence the physiology and patho-physiology of bone by activating osteoblasts and inhibiting osteoclast activity resulting in relative osteoprotection. Whether this influence is directly exerted by pituitary-derived TSH in vivo is less certain, because we have previously reported that the suppression of pituitary TSH does not remove such protection. Here, we have characterized the functional relevance of a novel form of the TSH-β subunit, designated TS ...[more]