Ontology highlight
ABSTRACT:
SUBMITTER: Handel AE
PROVIDER: S-EPMC3836167 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Handel Adam E AE Disanto Giulio G Ramagopalan Sreeram V SV
Expert review of neurotherapeutics 20130201 2
Next-generation sequencing techniques have made vast quantities of data on human genomes and transcriptomes available to researchers. Huge progress has been made towards understanding the basis of many Mendelian neurological conditions, but progress has been considerably slower in complex neurological diseases (multiple sclerosis, migraine, Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and so on). The authors review current next-generation sequencing methodologies and ...[more]