Retinocollicular mapping explained?
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ABSTRACT:
SUBMITTER: Sterratt DC
PROVIDER: S-EPMC3836172 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Publications
Retinocollicular mapping explained?
Sterratt David C DC Hjorth J J Johannes JJJ
Visual neuroscience 20130701 4
We review and comment on the recent model of Grimbert and Cang of the development of topographically ordered maps from the retina to the superior colliculus. This model posits a phase in which arbors are created in zones permitted by Eph and ephrin signaling, followed by a phase in which activity-dependent synaptic plasticity refines the map. We show that it is not possible to generate the arborization probability functions used in the simulations of Grimbert and Cang using gradients of Ephs and ...[more]
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