Ontology highlight
ABSTRACT:
SUBMITTER: Gordon MA
PROVIDER: S-EPMC3836679 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Gordon Michael A MA Zhang Wu W Yang Dongyun D Iqbal Syma S El-Khouiery Anthony A Nagashima Fumio F Lurje Georg G Labonte Melissa M Wilson Peter P Sherrod Andy A Ladner Robert D RD Lenz Heinz-Josef HJ
Pharmacogenomics 20110101 1
<h4>Aims</h4>Survival and response rates in metastatic colorectal cancer remain poor, despite advances in drug development. There is increasing evidence to suggest that gender-specific differences may contribute to poor clinical outcome. We tested the hypothesis that genomic profiling of metastatic colorectal cancer is dependent on gender.<h4>Materials & methods</h4>A total of 152 patients with metastatic colorectal cancer who were treated with oxaliplatin and continuous infusion 5-fluorouracil ...[more]