SdrA, a new DeoR family regulator involved in Streptomyces avermitilis morphological development and antibiotic production.
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ABSTRACT:
SUBMITTER: Ulanova D
PROVIDER: S-EPMC3837817 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
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SdrA, a new DeoR family regulator involved in Streptomyces avermitilis morphological development and antibiotic production.
Ulanova Dana D Kitani Shigeru S Fukusaki Eiichiro E Nihira Takuya T
Applied and environmental microbiology 20131011 24
The SAV3339 (SdrA) protein of Streptomyces avermitilis, a member of the DeoR family of regulators, was assessed to determine its in vivo function by gene knockdown through the use of cis-encoded noncoding RNA and knockout of the sdrA gene. These analyses revealed that SdrA represents another class of Streptomyces regulator that controls morphological development and antibiotic production. ...[more]
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