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Carbapenemase-producing enterobacteriaceae in Spain in 2012.


ABSTRACT: We report the epidemiological impact of carbapenemase-producing Enterobacteriaceae (CPE) in Spain in 2012. Of the 237 carbapenemases detected, 163 were from the OXA-48 group, 60 were from VIM-1, 8 were from KPC-2, 5 were from IMP, and 1 was from NDM-1. Interhospital spread of carbapenemase-producing Klebsiella pneumoniae was due to a limited number of multilocus sequence types (MLST) and carbapenemase types, including ST15-VIM-1, ST11-OXA-48, ST405-OXA-48, ST101-KPC-2, and ST11-VIM-1. The number of CPE cases in Spain has increased sharply in recent years, due mainly to the emergence of OXA-48.

SUBMITTER: Oteo J 

PROVIDER: S-EPMC3837857 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature

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Carbapenemase-producing enterobacteriaceae in Spain in 2012.

Oteo Jesús J   Saez David D   Bautista Verónica V   Fernández-Romero Sara S   Hernández-Molina Juan Manuel JM   Pérez-Vázquez María M   Aracil Belén B   Campos José J  

Antimicrobial agents and chemotherapy 20130916 12


We report the epidemiological impact of carbapenemase-producing Enterobacteriaceae (CPE) in Spain in 2012. Of the 237 carbapenemases detected, 163 were from the OXA-48 group, 60 were from VIM-1, 8 were from KPC-2, 5 were from IMP, and 1 was from NDM-1. Interhospital spread of carbapenemase-producing Klebsiella pneumoniae was due to a limited number of multilocus sequence types (MLST) and carbapenemase types, including ST15-VIM-1, ST11-OXA-48, ST405-OXA-48, ST101-KPC-2, and ST11-VIM-1. The number  ...[more]

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