Ontology highlight
ABSTRACT:
SUBMITTER: Welsch JC
PROVIDER: S-EPMC3838268 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Journal of virology 20131009 24
Measles virus (MV) infection causes an acute childhood disease that can include infection of the central nervous system and can rarely progress to severe neurological disease for which there is no specific treatment. We generated potent antiviral peptide inhibitors of MV entry and spreading and MV-induced cell fusion. Dimers of MV-specific peptides derived from the C-terminal heptad repeat region of the MV fusion protein, conjugated to cholesterol, efficiently protect SLAM transgenic mice from f ...[more]