Invaders: Recognition of Double-Stranded DNA by Using Duplexes Modified with Interstrand Zippers of 2'-O-(Pyren-1-yl)methyl-ribonucleotides.
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ABSTRACT:
SUBMITTER: Didion BA
PROVIDER: S-EPMC3838861 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Publications
Invaders: Recognition of Double-Stranded DNA by Using Duplexes Modified with Interstrand Zippers of 2'-O-(Pyren-1-yl)methyl-ribonucleotides.
Didion Bradley A BA Karmakar Saswata S Guenther Dale C DC Sau Sujay P SP Verstegen John P JP Hrdlicka Patrick J PJ
Chembiochem : a European journal of chemical biology 20130823 13
The invasion has begun: Invaders are shown to recognize DNA hairpins in cell-free assays and chromosomal DNA during non-denaturing fluorescence in situ hybridization (nd-FISH) experiments. As Invaders are devoid of inherent sequence limitations, many previously inaccessible DNA targets could become accessible to exogenous control with important ramifications for karyotyping, in vivo imaging, and gene regulation. ...[more]
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