Associations between white matter microstructure and cognitive performance in old and very old age.
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ABSTRACT:
SUBMITTER: Laukka EJ
PROVIDER: S-EPMC3839877 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
Associations between white matter microstructure and cognitive performance in old and very old age.
Laukka Erika J EJ Lövdén Martin M Kalpouzos Grégoria G Li Tie-Qiang TQ Jonsson Tomas T Wahlund Lars-Olof LO Fratiglioni Laura L Bäckman Lars L
PloS one 20131125 11
Increasing age is associated with deficits in a wide range of cognitive domains as well as with structural brain changes. Recent studies using diffusion tensor imaging (DTI) have shown that microstructural integrity of white matter is associated with cognitive performance in elderly persons, especially on tests that rely on perceptual speed. We used structural equation modeling to investigate associations between white matter microstructure and cognitive functions in a population-based sample of ...[more]
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