Ontology highlight
ABSTRACT:
SUBMITTER: Hnisz D
PROVIDER: S-EPMC3841062 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Hnisz Denes D Abraham Brian J BJ Lee Tong Ihn TI Lau Ashley A Saint-André Violaine V Sigova Alla A AA Hoke Heather A HA Young Richard A RA
Cell 20131010 4
Super-enhancers are large clusters of transcriptional enhancers that drive expression of genes that define cell identity. Improved understanding of the roles that super-enhancers play in biology would be afforded by knowing the constellation of factors that constitute these domains and by identifying super-enhancers across the spectrum of human cell types. We describe here the population of transcription factors, cofactors, chromatin regulators, and transcription apparatus occupying super-enhanc ...[more]