Ontology highlight
ABSTRACT:
SUBMITTER: Sidhu N
PROVIDER: S-EPMC3841409 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Sidhu N N Davies S S Nadarajah A A Rivera J J Whittington R R Mercier R J RJ Virag L L Wang S S Flood P P
British journal of anaesthesia 20130407 2
<h4>Background</h4>Activation of nicotinic receptors with nicotine has been shown to reduce post-surgical pain in clinical and preclinical studies. Choline is a selective agonist at α7-type nicotinic receptors that does not have addictive or sympathetic activating properties. It is anti-nociceptive in animal studies. We conducted a double-blind randomized trial of oral choline supplementation with lecithin to aid in the treatment of pain after gynaecological surgery.<h4>Methods</h4>Sixty women h ...[more]