Ontology highlight
ABSTRACT:
SUBMITTER: Iadecola C
PROVIDER: S-EPMC3842016 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Vascular cognitive impairment defines alterations in cognition, ranging from subtle deficits to full-blown dementia, attributable to cerebrovascular causes. Often coexisting with Alzheimer's disease, mixed vascular and neurodegenerative dementia has emerged as the leading cause of age-related cognitive impairment. Central to the disease mechanism is the crucial role that cerebral blood vessels play in brain health, not only for the delivery of oxygen and nutrients, but also for the trophic signa ...[more]