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Photoredox Activation and Anion Binding Catalysis in the Dual Catalytic Enantioselective Synthesis of ?-Amino Esters.

ABSTRACT: The enantioselective oxidative C-H functionalization of tetrahydroisoquinoline derivatives is achieved through the merger of photoredox and asymmetric anion-binding catalysis. This combination of two distinct catalysis concepts introduces a potentially general approach to asymmetric transformations in oxidative photocatalysis.

SUBMITTER: Bergonzini G

PROVIDER: S-EPMC3842187 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature

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Photoredox Activation and Anion Binding Catalysis in the Dual Catalytic Enantioselective Synthesis of β-Amino Esters.

Bergonzini Giulia G Schindler Corinna S CS Wallentin Carl-Johan CJ Jacobsen Eric N EN Stephenson Corey R J CR

Chemical science 20140101 1

The enantioselective oxidative C-H functionalization of tetrahydroisoquinoline derivatives is achieved through the merger of photoredox and asymmetric anion-binding catalysis. This combination of two distinct catalysis concepts introduces a potentially general approach to asymmetric transformations in oxidative photocatalysis. ...[more]

PMID: 24294480

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