Promoter methylation of tumor suppressor genes in esophageal squamous cell carcinoma.
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ABSTRACT:
SUBMITTER: Li JS
PROVIDER: S-EPMC3845589 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Publications
Promoter methylation of tumor suppressor genes in esophageal squamous cell carcinoma.
Li Ji-Sheng JS Ying Jian-Ming JM Wang Xiu-Wen XW Wang Zhao-Hui ZH Tao Qian Q Li Li-Li LL
Chinese journal of cancer 20120508 1
Esophageal squamous cell carcinoma (ESCC) is a prevalent and fatal cancer in China and other Asian countries. Epigenetic silencing of key tumor suppressor genes (TSGs) is critical to ESCC initiation and progression. Recently, many novel TSGs silenced by promoter methylation have been identified in ESCC, and these genes further serve as potential tumor markers for high-risk group stratification, early detection, and prognosis prediction. This review summarizes recent discoveries on aberrant promo ...[more]
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