Pharmacovigilance using clinical notes.
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ABSTRACT:
SUBMITTER: LePendu P
PROVIDER: S-EPMC3846296 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Publications
Pharmacovigilance using clinical notes.
LePendu P P Iyer S V SV Bauer-Mehren A A Harpaz R R Mortensen J M JM Podchiyska T T Ferris T A TA Shah N H NH
Clinical pharmacology and therapeutics 20130304 6
With increasing adoption of electronic health records (EHRs), there is an opportunity to use the free-text portion of EHRs for pharmacovigilance. We present novel methods that annotate the unstructured clinical notes and transform them into a deidentified patient-feature matrix encoded using medical terminologies. We demonstrate the use of the resulting high-throughput data for detecting drug-adverse event associations and adverse events associated with drug-drug interactions. We show that these ...[more]
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