Ontology highlight
ABSTRACT:
SUBMITTER: Arendt CS
PROVIDER: S-EPMC3851587 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Molecular and biochemical parasitology 20131010 2
Most eukaryotic organisms including protozoans like Crithidia, Leishmania, and Plasmodium encode a repertoire of equilibrative nucleoside transporters (ENTs). Using genomic sequencing data from Crithidia fasciculata, we discovered that this organism contains multiple ENT genes of highly similar sequence to the previously cloned and characterized adenosine transporter CfNT1: CfAT1 and CfNT3, and an allele of CfAT1, named CfAT1.2. Characterization of CfAT1 shows that it is an adenosine-only transp ...[more]